• Broker Jinny Saad 5129617336
  • Broker Connor Chatlos 5132551111

Villa Rosa Medical Plaza 5131 Medical Dr 8,000 - 31,467 SF of Medical Space Available in San Antonio, TX 78229

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HIGHLIGHTS

  • Prime Medical Space: Offering 30,270 SF of customizable, Class A medical space in a modern facility.
  • Ample Parking: Provides 100 surface spaces and 20 covered spaces, ensuring convenient access for patients and staff alike.
  • Certified for Overnight Stays: Approved for overnight patient stays, making it ideal for a range of medical specialties.
  • Centrally located in the heart of South Texas Medical Center, near top-tier hospitals like Christus Santa Rosa, Methodist, St. Luke's.

ALL AVAILABLE SPACES(3)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor, Ste 200
  • 8,000-8,217 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Shell Space
  • Now

San Antonio Medical Center Full floor opportunity Shell space Building signage available Certified for patient overnight stay

  • Fits 57 - 183 People
  • 4228-Suite200
  • 2nd Floor, Ste 210
  • 14,788 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Shell Space
  • Now
  • 4228-Suite210
  • 3rd Floor, Ste 300
  • 8,462 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Shell Space
  • Now
  • 4228-Suite300
  • 4228-Villa Rosa Beyondview Flyer
Space Size Term Rental Rate Space Use Condition Available
2nd Floor, Ste 200 8,000-8,217 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Medical Shell Space Now
2nd Floor, Ste 210 14,788 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Medical Shell Space Now
3rd Floor, Ste 300 8,462 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Medical Shell Space Now

2nd Floor, Ste 200

Size
8,000-8,217 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Shell Space
Available
Now

2nd Floor, Ste 210

Size
14,788 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Shell Space
Available
Now

3rd Floor, Ste 300

Size
8,462 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Shell Space
Available
Now

2nd Floor, Ste 200

Size 8,000-8,217 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Shell Space
Available Now

San Antonio Medical Center Full floor opportunity Shell space Building signage available Certified for patient overnight stay

  • Fits 57 - 183 People
  • 4228-Suite200

2nd Floor, Ste 210

Size 14,788 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Shell Space
Available Now

  • 4228-Suite210

3rd Floor, Ste 300

Size 8,462 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Shell Space
Available Now

  • 4228-Suite300
  • 4228-Villa Rosa Beyondview Flyer

PROPERTY OVERVIEW

Villa Rosa Medical Plaza is a 68,402 SF state-of-the-art medical office building located on Medical Drive, right in the center of South Texas Medical Center. Built in 2010, this Class A facility provides modern infrastructure with a sustainable design. Certified for overnight patient stays, this plaza is ideal for a variety of medical tenants seeking convenience and cutting-edge amenities. Its prime location offers immediate proximity to San Antonio’s leading hospital systems, including Christus Santa Rosa, Methodist, St. Luke's, and University Health, making it the perfect location for medical professionals.

  • Bus Line

PROPERTY FACTS

Building Type
Office
Year Built
2010
Building Height
3 Stories
Building Size
68,402 SF
Building Class
B
Typical Floor Size
22,801 SF
Unfinished Ceiling Height
12’
Parking
100 Surface Parking Spaces
20 Covered Parking Spaces

ATTACHMENTS

4228-Villa Rosa Beyondview Flyer 7-1-24 (1)

LINKS

  • Beyond View Virtual Space Plan

MAP

ADDITIONAL PHOTOS

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View Photo 5131_Medical_Dr_San_Antonio_TX_78229_USA-Foyer-8G5A1377 - Copy
View Photo 5131_Medical_Dr_San_Antonio_TX_78229_USA-Foyer-8G5A1365 - Copy
View Photo Building Photo
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  • Listing ID: 30979117

  • Date on Market: 5/28/2025

  • Last Updated: 5/28/2025

  • Address: 5131 Medical Dr, San Antonio, TX 78229